I-Best NMN powder (1094-61-7) Umkhiqizi nefektri

I-NMN powder (1094-61-7)

April 7, 2020

ICofttek ingumkhiqizi omuhle kakhulu we-NMN e-China. Ifektri yethu inohlelo oluphelele lokuphathwa kokukhiqiza (i-ISO9001 & ISO14001), enekhono lokukhiqiza lenyanga elingu-2400kg.

 


Isimo: Ekukhiqizeni kweMisa
Iyunithi: 1kg / isikhwama, 25kg / Drum

I-NMN powder (1094-61-7) ividiyo

 

I-NMN powder Siziqu

Igama: I-β-Nicotinamide Mononucleotide (NMN)
CAS: 1094-61-7
Ukuhlanzeka 98%
Ifomula Yamamolekhula: C11H15N2O8P
Isisindo Yamamolekhula: I-334.2208 g / mol
I-Melt Point: > 96 ° C
Igama lamakhemikhali: ((2R,3S,4R,5R)-5-(3-carbamoylpyridin-1-ium-1-yl)-3,4-dihydroxytetrahydrofuran-2-yl)methyl hydrogen phosphate
omqondofana: INicotinamide Mononucleotide; NMN; β-NMN; I-Nic-Nicotinamide mononucleotide
InChI Key: DAYLJWODMCOQEW-TURQNECASA-N
Ukuphila okungaphelele: N / A
Umswakama: I-soluble e-DMSO, Methanol, Amanzi
Isimo Sokugcina: 0 - 4 C isikhathi esifushane (izinsuku kuya emavikini), noma -20 C isikhathi eside (izinyanga)
Isicelo: I-Nicotinamide mononucleotide (NMN) isuselwa ku-B-uvitamini niacin othuthukisa ngokumangazayo impilo kanye nokuphila isikhathi eside ngokusebenza njengokwandulelwa kwe-NAD +, ikhempulethi ebamba iqhaza elibalulekile ekwenziweni kwamandla, kumetabolism, kanye nkulumo ye-gene emzimbeni.
ukubukeka: powder emhlophe

 

I-NMN (1094-61-7) I-NMR Spectrum

I-NMN (1094-61-7) - I-NMR Spectrum

Uma udinga i-COA, i-MSDS, i-HNMR yeqoqwana ngalinye lomkhiqizo nolunye ulwazi, sicela uxhumane nathi umphathi wezentengiso.

 

Yini i-β-Nicotinamide Mononucleotide (NMN) CAS 1094-61-7?

I-Nicotinamide Mononucleotide, eyaziwa nangokuthi (“NMN” ne- “β-NMN”) iyi-nucleotide etholakala ku-ribose ne-nicotinamide Njenge-nicotinamide riboside, i-NMN isuselwa ku-niacin, futhi abantu bane-enzyme abangasebenzisa i-NMN ukukhiqiza i-nicotinamide adenine dinucleotide ( I-NADH). Ngoba i-NADH iyi-cofactor yezinqubo ngaphakathi kwe-mitochondria, i-sirtuins, ne-PARP, i-NMN ifundwe ngezinhlobo zezilwane njenge-ejenti engavimbela ukuvikela nokuguga.

 

Izinzuzo ze-β-Nicotinamide Mononucleotide (NMN) CAS 1094-61-7

Ucwaningo lwe-anti-ukuguga lukhombisile ukuthi ukungezelelwa nge-NMN, i-NAD + esemqoka ephakathi, kuyasebenza ekunciphiseni ukwehla okuhlobene nomzimba okuhlobene nobudala futhi kunciphise ukuqhubeka kwezifo eziningi ezihlobene nobudala. I-NMN inemiphumela ezuzisayo ekukhiqizweni kwamandla ezingeni lamaselula, ithuthukisa ukubekezelela ushukela, inciphisa ukuvuvukala, isiza ukugcina uhlelo lokujikeleza, ilungisa iDNA, futhi inemiphumela ezuzisayo ekongeni umsebenzi wokuqonda. I-NMN ikhombisile futhi amandla njenge-ejenti yokwelapha emelana nokuphazamiseka kwe-neurodegenerative ejwayelekile ekugugeni. Ukungezelelwa nge-NMN kungakusiza ekulondolozeni ukukhuthazela kanye nokuhamba. Ukulondolozwa kwemisebenzi yalezi zinhlelo ezehlukene emzimbeni kukhuthaza impilo nempilo ende futhi kuthuthukisa kakhulu impilo yempilo njengoba ukuguga kuqhubeka.

 

I-β-Nicotinamide Mononucleotide (NMN) CAS 1094-61-7 I-Mechanism Of Action?

I-β-Nicotinamide Mononucleotide (i-NMN) iphakathi kwe-NAD + biosynthesis ekhiqizwe kusuka ku-nicotinamide nge-nicotinamide phosphoribosyltransferase (NAMPT) futhi ebizwa nangokuthi yi-NMN noma i-nicotinamide ribotide. Ezifundweni zakamuva zezicelo ze-NMN zokuvimbela nokuxilonga izifo ezincike eminyakeni yobudala ezinjengesifo sikashukela, isifo se-neurodegenerative, isifo senhliziyo njll.

 

I-β-Nicotinamide Mononucleotide (NMN) CAS 1094-61-7 Isicelo

I-β-Nicotinamide Mononucleotide (NMN) inemiphumela ezuzisayo ekusebenzeni kwe-metabolism emzimbeni wonke, kufaka phakathi imiphumela emihle emithanjeni yamathambo, ukusebenza kwesibindi, ukuqina kwamathambo, ukusebenza kwamehlo, ukuzwela kwe-insulin, ukusebenza komzimba, amazinga omzimba, kanye namazinga omsebenzi.

 

I-NMN powder ukudayiswa(Ungayithenga kuphi i-β-Nicotinamide Mononucleotide (NMN) powder ngobuningi)

Inkampani yethu ithokozela ubudlelwane besikhathi eside namakhasimende ethu ngoba sigxile ekusebenzeni kwamakhasimende nokunikezela ngemikhiqizo emihle. Uma unentshisekelo ngomkhiqizo wethu, siyavumelana nezimo nge-oda eyenziwe ngokwezifiso ukuze ivumelane nesidingo sakho esithile nesikhathi sethu sokuhola esisheshayo kuma-oda siqinisekisa ukuthi uzowunambitha kakhulu umkhiqizo wethu ngesikhathi. Siphinde sigxile nezinsizakalo ezingezwe zenani. Sitholakala ngemibuzo yensiza nolwazi lokuxhasa ibhizinisi lakho.

Singumhlinzeki we-β-Nicotinamide Mononucleotide (NMN) we-powder iminyaka eminingi, sinikezela ngemikhiqizo ngentengo yokuncintisana, futhi umkhiqizo wethu usezingeni eliphezulu kakhulu futhi uhlolwa ngokuqinile, ngokuzimela ukuqinisekisa ukuthi kuphephile ukusetshenziswa emhlabeni wonke.

 

Okubhekwayo

  • I-kiss T, i-Balasubramanian P, i-Valcarcel-Ares MN, iTarantini S, i-Yabluchanskiy A, uCsipo T, i-Lipecz A, i-Reglodi D, i-Zhang XA, i-Bari F, i-Farkas E, i-Csiszar A, i-Ungvari Z. Nicotinamide mononucleotide (NMN) ifaka uxinzelelo lwe-oxidative futhi isindise umthamo we-angiogenic kumaseli asekhulile we-cerebromicrovascular endothelial: indlela engahle ivikeleke kokulimazeka kokulimazeka kwemisipha. I-Geroscience. 2019 Meyi 29. doi: 10.1007 / s11357-019-00074-2. I-PubMed PMID: 31144244.
  • Lukacs M, Gilley J, Zhu Y, Orsomando G, Angeletti C, Liu J, Yang X, Park J, Hopkin RJ, MPleman Coleman, Zhai RG, Stottmann RW. Izinguquko ezinkulu zokulahlekelwa-kokusebenza okubucayi kwe-nicotinamide mononucleotide adenylyltransferase 2 (NMNAT2) ezingxenyeni ezimbili zokulandelana kokuguqulwa kwe-fetus akinesia. I-Exp Neurol. 2019 Meyi 25: 112961. doi: 10.1016 / j.expneurol.2019.112961.PubMed PMID: 31136762.
  • IGrozio A, Mills KF, Yoshino J, Bruzzone S, Sociali G, Tokizane K, Lei HC, Cunningham R, Sasaki Y, Migaud ME, Imai SI. I-Slc12a8 isishiphu se-nicotinamide mononucleotide transporter. Nat Metab. I-2019 Jan; 1 (1): 47-57. doi: 10.1038 / s42255-018-0009-4. Epub 2019 Jan 7. I-PubMed PMID: 31131364; I-PubMed Central PMCID: PMC6530925.

 


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