Umkhiqizi ohamba phambili we-Alpha Lipoic Acid (ALA) - uCofttek

I-Alpha Lipoic Acid (ALA)

April 20, 2021

ICofttek ingumkhiqizi we-Alpha Lipoic Acid (ALA) omuhle kakhulu eChina. Ifektri yethu inohlelo oluphelele lokuphathwa kokukhiqiza (i-ISO9001 & ISO14001), enekhono lokukhiqiza lanyanga zonke elingu-1000kg.

 


Isimo: Ekukhiqizeni kweMisa
Iyunithi: 1kg / isikhwama, 25kg / Drum

I-Alpha Lipoic Acid (ALA) (1077-28-7) Siziqu

Igama: I-Alpha Lipoic Acid (ALA)
CAS: 1077-28-7
Ukuhlanzeka 98%
Ifomula Yamamolekhula: C8H14O2S2
Isisindo Yamamolekhula: I-206.33 g / mol
I-Melt Point: I-60-62 ° C (140-144 ° F; 333-335 K)
Igama lamakhemikhali: (R) -5- (1,2-Dithiolan-3-yl) i-pentanoic acid;

α-Lipoic acid; I-alpha lipoic acid; I-Thioctic acid; I-6,8-Dithiooctanoic acid

omqondofana: (±) -α-Lipoic acid, (±) -1,2-Dithiolane-3-pentanoic acid, 6,8-Dithiooctanoic acid, DL -α-Lipoic acid, DL -6,8-Thioctic acid, Lip (S2 )
InChI Key: Ingxenye #: AGBQKNBQESQNJD-UHFFFAOYSA-N
Ukuphila okungaphelele: Impilo uhhafu we-ALA elawulwa ngomlomo imane ingama-30 min
Umswakama: Incibilika Kancane Kakhulu emanzini (0.24 g / L); Ukuncibilika ku-ethanol 50 mg / mL
Isimo Sokugcina: 0 - 4 C isikhathi esifushane (izinsuku kuya emavikini), noma -20 C isikhathi eside (izinyanga)
Isicelo: I-alpha-lipoic acid isetshenziswa emzimbeni ukudiliza ama-carbohydrate nokwenza amandla kwezinye izitho zomzimba. I-Alpha-lipoic acid ibonakala isebenza njenge-antioxidant, okusho ukuthi ingahlinzeka ngokuvikelwa ebuchosheni ngaphansi kwezimo zokulimala noma zokulimala.
ukubukeka: Amakristalu aphuzi afana nezinaliti

 

I-Alpha Lipoic Acid (ALA) (1077-28-7) I-NMR Spectrum

 

I-Alpha Lipoic Acid (ALA) (1077-28-7) - I-NMR Spectrum

Uma udinga i-COA, i-MSDS, i-HNMR yeqoqwana ngalinye lomkhiqizo nolunye ulwazi, sicela uxhumane nathi umphathi wezentengiso.

 

I-Alpha Lipoic Acid (ALA) (1077-28-7)?

I-Alpha-lipoic acid iyinhlanganisela etholakala ngokwemvelo ngaphakathi kwawo wonke amaseli omzimba womuntu. Indima yawo eyinhloko ukuguqula ushukela wegazi (i-glucose) ube ngamandla usebenzisa i-oxygen, inqubo ebizwa ngokuthi yi-aerobic metabolism. I-Alpha-lipoic acid nayo ibhekwa njenge-antioxidant, okusho ukuthi inganciphisa izinhlanganisela eziyingozi ezibizwa ngama-radicals amahhala alimaza amaseli ezingeni lezakhi zofuzo.

Okwenza i-alpha-lipoic acid ihluke kakhulu ukuthi iyancibilika emanzini nakumafutha. Lokho kusho ukuthi ingaletha amandla ngokushesha noma iwagcine ukuze isetshenziswe ngokuzayo.

I-Alpha-lipoic acid nayo ingavuselela ama-antioxidants "asetshenzisiwe", kufaka phakathi i-vitamin C, i-vitamin E, kanye ne-amino acid eyaziwayo eyaziwa ngokuthi i-glutathione.1 Noma nini lapho lawa ma-antioxidants ehlisa i-radical yamahhala, ayaphazamisa futhi abe ngama-radicals mahhala ngokwawo. I-alpha-lipoic acid isiza ukuyibuyisa ngokumunca ama-electron amaningi nokuyiguqulela emuva kwifomu layo elizinzile.

I-Alpha-lipoic acid kwesinye isikhathi ithathwa njengesengezo ngaphansi kokucatshangwa ukuthi ingathuthukisa imisebenzi ethile ye-metabolic, kufaka phakathi ukushiswa kwamafutha, ukukhiqizwa kwe-collagen, nokulawulwa kweglucose egazini. Kunobufakazi obukhulayo bokungenani kwalezi zimangalo.

 

Izinzuzo ze-Alpha Lipoic Acid (ALA) (1077-28-7)

Diabetes

Kudala kucatshangwa ukuthi i-alpha-lipoic acid ingasiza ekulawuleni i-glucose ngokwandisa ijubane lapho ushukela wegazi uhlanganiswa khona. Lokhu kungasiza ekwelapheni isifo sikashukela, isifo esibonakala ngamazinga aphezulu eglucose egazini ngokungajwayelekile.

Ukubuyekezwa okuhlelekile kwe-2018 kanye nokuhlaziywa kwe-meta kwezilingo ezingama-20 ezilawulwa ngokungahleliwe zabantu abanezifo ze-metabolic (abanye babene-type 2 yesifo sikashukela, abanye babenezinye izifo zokuphazamiseka komzimba) bathola ukuthi i-lipoic acid supplementation yehlisa ukuzila kwegazi kweglucose, ukugxilwa kwe-insulin, ukumelana ne-insulin, kanye ne-hemoglobin yegazi Amazinga we-A1C.

 

Ubuhlungu Bobuhlungu

I-Neuropathy yigama lezokwelapha elisetshenziselwa ukuchaza ubuhlungu, ukuba ndikindiki, nokuzwa okungavamile okubangelwa ukulimala kwezinzwa. Imvamisa, umonakalo ubangelwa yingcindezi ene-oxidative ebekwe emithanjeni izifo ezingalapheki ezinjengesifo sikashukela, isifo seLyme, usiba, isifo se-thyroid, ukwehluleka kwezinso ne-HIV.

Abanye bakholelwa ukuthi i-alpha-lipoic acid, enikezwa ngemithamo emikhulu ngokwanele, ingamelana nalokhu kucindezeleka ngokusebenzisa amandla e-antioxidant. Kube khona ubufakazi balo mphumela kubantu abane-neuropathy yesifo sikashukela, isimo esingahle sithikameze abantu abanesifo sikashukela esithuthukile.

Ukubuyekezwa kwezifundo ezivela eNetherlands ngo-2012 kuphethe ngokuthi isilinganiso somjovo we-alpha-lipoic acid osetshenziswa nsuku zonke ngama-600-mg onikezwa ngaphezu kwamasonto amathathu unikeze "ukwehliswa okuphawulekayo nokwelashwa okuhambisana nobuhlungu be-neuropathic."

Njengasezifundweni zangaphambilini zesifo sikashukela, izengezo zomlomo ze-alpha-lipoic acid ngokuvamile zazingasebenzi kahle noma zazingenamphumela nhlobo.

 

Weight Loss

Ikhono le-alpha-lipoic acid lokukhulisa ukushisa kwamakhalori kanye nokukhuthaza ukulahleka kwesisindo liye lenziwa ihaba ngama-gurus amaningi okudla kanye nabakhiqizi bezithako. Uma kushiwo lokho, kukhona ubufakazi obukhulayo bokuthi i-alpha-lipoic acid ingathonya isisindo, noma ngabe ngesizotha.

Ukubuyekezwa kwezifundo zango-2017 zaseYale University kutholakale ukuthi izengezo ze-alpha-lipoic acid, ezisukela kumthamo osukela ku-300 kuye ku-1,800 mg nsuku zonke, zisize ukukhuthaza ukwehla kwesisindo esiphakathi kwamakhilogremu angu-2.8 uma kuqhathaniswa ne-placebo.

Kwakungekho ukuhlangana phakathi komthamo wokungezelela we-alpha-lipoic nenani lokwehla kwesisindo. Ngaphezu kwalokho, isikhathi sokwelashwa sibonakala sithonya inkomba yomzimba womuntu (BMI), kodwa hhayi isisindo sangempela somuntu.

Lokhu kusho ukuthi, ngenkathi kubonakala ungalahlekelwa isisindo esiningi nge-alpha-lipoic acid, ukwakheka komzimba wakho kungathuthuka njengoba kancane kancane amafutha esuswa yimisipha emile.

 

Cholesterol High

I-Alpha-lipoic acid sekukholakala ukuthi ithonya isisindo nempilo ngokuguqula ukwakheka kwe-lipid (fat) egazini. Lokhu kufaka phakathi ukwandisa "okuhle" kwe-high-density lipoprotein (HDL) cholesterol ngenkathi kwehliswa "okubi" kwe-cholesterol ephansi ye-lipoprotein (LDL) ne-triglycerides. Ucwaningo lwamuva lubonisa ukuthi lokhu kungenzeka kungabi njalo.

Ocwaningweni lwango-2011 oluvela eKorea, abantu abadala abayi-180 banikeze i-1,200 kuya ku-1,800 mg ye-alpha-lipoic acid elahlekelwe isisindo esingamaphesenti angama-21 kuneqembu le-placebo ngemuva kwamasonto angama-20 kepha ayikaze ithuthuke ku-cholesterol ephelele, i-LDL, i-HDL, noma i-triglycerides.

Eqinisweni, amanani aphakeme we-alpha-lipoic acid anikezwe ukwanda kwe-cholesterol ephelele ne-LDL kubahlanganyeli besifundo.

 

Isikhumba Esilimele Ilanga

Abakhiqizi bezimonyo bavame ukuthanda ukuziqhayisa ngokuthi imikhiqizo yabo iyazuza ezakhiweni "zokulwa nokuguga" ze-alpha-lipoic acid. Ucwaningo luphakamisa ukuthi kungahle kube nokukholelwa kulezi zimangalo. I-athikili yokubukeza iphawula ukuthi iyi-antioxidant enamandla futhi ifundelwe imiphumela yayo yokuvikela ekulimaleni kwemisebe.

 

I-Alpha Lipoic Acid (ALA) (1077-28-7) kusebenzisa?

I-Alpha-lipoic acid noma i-ALA iyinhlanganisela eyenzeka ngokwemvelo eyenziwe emzimbeni. Isebenza imisebenzi ebalulekile ezingeni lamaselula, njengokukhiqizwa kwamandla. Uma nje uphilile, umzimba ungakhiqiza yonke i-ALA eyidingayo ngalezi zinhloso. Ngaphandle kwalokhu, kube nentshisekelo yakamuva ekusebenziseni izithasiselo ze-ALA. Abameli be-ALA benza izimangalo ezisukela emiphumeleni enenzuzo yokwelapha izimo ezinjengesifo sikashukela ne-HIV ekuthuthukiseni ukuncipha komzimba.

 

I-Alpha Lipoic Acid (ALA) (1077-28-7) Isikali

Ngenkathi ithathwa njengephephile, ayikho imihlahlandlela eqondisa ukusetshenziswa okufanele kwe-alpha-lipoic acid. Izithako eziningi zomlomo zithengiswa ngokwakhiwa okusukela ku-100 kuye ku-600 mg. Ngokuya ngobuningi bobufakazi bamanje, isilinganiso esiphezulu sansuku zonke esifinyelela ku-1,800 mg kucatshangwa ukuthi siphephile kubantu abadala.

Uma kushiwo lokho, konke kusuka esisindweni somzimba nobudala kuya ekusebenzeni kwesibindi nokusebenza kwezinso kungathinta okuphephile kuwe njengomuntu ngamunye. Njengomthetho ojwayelekile wesithupha, phutha ohlangothini lokuqapha futhi uhlale ukhetha umthamo ophansi.

Izithako ze-alpha lipoic acid zingatholakala ku-inthanethi nasezitolo eziningi zokudla ezempilo nasezitolo zemithi. Ukuze uthole ukumuncwa okuphezulu, izithasiselo kufanele zithathwe esiswini esingenalutho.

 

I-Alpha-lipoic Acid powder ukudayiswa(Ungathenga kuphi i-Alpha-lipoic Acid powder ngobuningi)

Inkampani yethu ithokozela ubudlelwane besikhathi eside namakhasimende ethu ngoba sigxile ekusebenzeni kwamakhasimende nokunikezela ngemikhiqizo emihle. Uma unentshisekelo ngomkhiqizo wethu, siyavumelana nezimo nge-oda eyenziwe ngokwezifiso ukuze ivumelane nesidingo sakho esithile nesikhathi sethu sokuhola esisheshayo kuma-oda siqinisekisa ukuthi uzowunambitha kakhulu umkhiqizo wethu ngesikhathi. Siphinde sigxile nezinsizakalo ezingezwe zenani. Sitholakala ngemibuzo yensiza nolwazi lokuxhasa ibhizinisi lakho.

Singumhlinzeki we-Alpha-lipoic Acid powder oqeqeshiwe iminyaka eminingana, sinikezela ngemikhiqizo ngamanani aphansi, futhi umkhiqizo wethu ungowekhwalithi ephezulu kakhulu futhi uhlolwa ngokuqinile, nokuzimela ukuqinisekisa ukuthi kuphephile ukusetshenziswa emhlabeni wonke.

 

Okubhekwayo

  1. IHaenen, GRMM; UBast, A (1991). "Ukuqhekeka kwe-asidi eyi-hypochlorous nge-lipoic acid". I-Biochemical Pharmacology. 42 (11): 2244-6. i-doi: 10.1016 / 0006-2952 (91) 90363-A. I-PMID 1659823.
  2. Biewenga, GP; IHaenen, GR; IBast, A (Septhemba 1997). "I-pharmacology ye-antioxidant lipoic acid". I-General Pharmacology. 29 (3): 315-31. i-doi: 10.1016 / S0306-3623 (96) 00474-0. I-PMID 9378235.
  3. UShuphupke, H; IHempel, R; UPeter, G; UHermann, R; et al. (Juni 2001). "Izindlela ezintsha ze-metabolic ze-alpha-lipoic acid". Izidakamizwa Nezidakamizwa. 29 (6): 855-62. I-PMID 11353754.
  4. Acker, DS; UWayne, WJ (1957). "Ama-α-lipoic acid asebenzayo futhi asebenzayo". Ijenali yeAmerican Chemical Society. 79 (24): 6483-6487. i-doi: 10.1021 / ja01581a033.
  5. UHornberger, CS; I-Heitmiller, i-RF; IGunsalus, IC; ESchnakenberg, GHF; et al. (1952). "Ukulungiselela okwenziwe nge-lipoic acid". Ijenali yeAmerican Chemical Society. 74 (9): 2382. doi: 10.1021 / ja01129a511.