Khipha ku-internet GABA powder (56-12-2) Factory factory

I-GABA powder (56-12-2)

Kwangathi 19, 2021

ICofttek ingumkhiqizi wempuphu omuhle kakhulu weGamma-aminobutyric acid (GABA) eChina. Ifektri yethu inohlelo oluphelele lokuphathwa kokukhiqiza (i-ISO9001 & ISO14001), enomthamo wokukhiqiza wanyanga zonke ongu-260kg.


Isimo: Ekukhiqizeni kweMisa
Iyunithi: 1kg / isikhwama, 25kg / Drum

Siziqu

Igama: I-Gamma-aminobutyric acid (GABA)
CAS: 56-12-2
Ukuhlanzeka 98%
Ifomula Yamamolekhula: C4H9NO2
Isisindo Yamamolekhula: I-103.120 g / mol
I-Melt Point: 203.7 ° C
Igama lamakhemikhali: I-4-aminobutanoic acid
omqondofana: I-4-Aminobutanoic acid

i-gamma-aminobutyric acid

Gaba

InChI Key: I-BTCSSZJGUNDROE-UHFFFAOYSA-N
Ukuphila okungaphelele: N / A
Umswakama: Incibilika emanzini (130 g / 100 ml)
Isimo Sokugcina: 0 - 4 C isikhathi esifushane (izinsuku kuya emavikini), noma -20 C isikhathi eside (izinyanga)
Isicelo: I-GABA ibhekwa njenge-neurotransmitter engavimbeli ngoba ivimba, noma ivimbela, amasiginali athile obuchopho futhi yehlise umsebenzi ohlelweni lwakho lwezinzwa.
ukubukeka: i-powder emhlophe ye-microcrystalline

 

I-Gamma-aminobutyric acid (GABA) (56-12-2) I-NMR Spectrum

IGamma-aminobutyric acid (GABA) (56-12-2) NMR Spectrum

Uma udinga i-COA, i-MSDS, i-HNMR yeqoqwana ngalinye lomkhiqizo nolunye ulwazi, sicela uxhumane nathi umphathi wezentengiso.

 

Yini iGamma-aminobutyric acid?

IGamma aminobutyric acid (GABA) iyi-amino acid eyenzeka ngokwemvelo esebenza njenge-neurotransmitter ebuchosheni bakho. Ama-Neurotransmitters asebenza njengezithunywa zamakhemikhali. I-GABA ibhekwa njenge-neurotransmitter engavimbeli ngoba ivimba, noma ivimbela, amasiginali athile obuchopho futhi yehlise umsebenzi ohlelweni lwakho lwezinzwa.

I-Gamma-aminobutyric acid (GABA) powder iyi-neurotransmitter engapheli elawula ukuthokomala kwe-neuronal, ithoni yemisipha, ukukhula kwamaseli we-stem, ukukhula kwengqondo kanye nemizwa. Ngesikhathi sokuthuthuka, i-GABA isebenza njenge-neurotransmitter ejabulisayo kepha ishintshela kamuva emsebenzini wokuvimbela. I-GABA ikhombisa imisebenzi ye-anxiolytic, anticonvulsant, kanye ne-amnestic, inciphisa ukuphumula nokunciphisa ukukhathazeka kuzilungiselelo zomtholampilo. Indima yayo eyinhloko ukunciphisa ukujabula kwe-neuronal kulo lonke uhlelo lwezinzwa. I-GABA ithengiswa njengesengezo sokudla.

 

Izinzuzo ze-GABA (56-12-2)

GABA yokulala

"I-GABA yenza umzimba nengqondo zikhululeke futhi zilale futhi zilale kahle ubusuku bonke," kusho uMichael J. Breus, Ph.D., isazi sokusebenza kwengqondo emitholampilo kanye nochwepheshe wokulala oqinisekiswe yibhodi. Ama-receptors we-GABA-A abuye abonakaliswe kakhulu kwi-thalamus, indawo yobuchopho ebandakanyeka ezinhlelweni zokulala, futhi ocwaningweni olulodwa, iziguli ezinokuqwasha zazinamazinga we-GABA acishe abe ngama-30% aphansi kunabantu abangenayo inkinga yokulala.

Ocwaningweni lwakamuva, ababambiqhaza abathathe i-100 mg yohlobo lwemvelo lwe-GABA (PharmaGABA) ngaphambi kokulala balala ngokushesha futhi balala kangcono ngemuva kwesonto elilodwa lokungezelelwa.

“Uma umzimba wakho ukhiqiza i- [GABA], isimiso sakho sezinzwa esiyinhloko siyehla, okwenza umuntu azizwe ekhululekile, futhi ezimweni eziningi ulele. Empeleni, iningi lezinsiza-kusebenza zokulala zisekela amazinga ejwayelekile e-GABA ebuchosheni, ”kusho uBreus.

Ngokwengeziwe, ukwesekwa nge-magnesium, okuyi-GABA agonist (okungukuthi, into ebopha ama-GABA receptors futhi ibenze basebenze ngendlela efanayo ne-GABA, kuchaza uRuhoy), kukhonjisiwe ukusekela ikhwalithi yokulala.

 

I-GABA yokucindezela nemicabango ekhathazayo

Ngokunikezwa kweqhaza le-GABA ekulinganiseni imiphumela ejabulisayo ye-glutamine, kucatshangwa ukuthi kuyasiza futhi ukugcina imizwa yengcindezi ihlolwe (yingakho izidakamizwa eziningi ezilwa nokukhathazeka ziqonde ngqo kuma-GABA-A receptors). Ucwaningo oluningi lukhombisa ukuthi amazinga we-GABA anele angadala kanjani imiphumela yokuthula.

Kwesinye isifundo esincane, abacwaningi babenabahlanganyeli abadla amanzi acolisisiwe, amanzi acolisisiwe nge-L-theanine (isakhi sokuthoba itiye eliluhlaza), noma amanzi acolisisiwe anohlobo lwemvelo lwe-GABA (PharmaGABA). Ngemuva kwemizuzu engamashumi ayisithupha, balinganisa amagagasi abo obuchopho nge-electroencephalogram (EEG) test futhi bathola ukuthi i-GABA inyuse kakhulu ama-alpha brainwaves wababambiqhaza (avame ukwenziwa esimweni esikhululekile) futhi anciphise ama-beta brainwaves (ngokuvamile abonakala ezimweni ezicindezelayo) kuqhathaniswa no-L -theanine noma amanzi.

Kokunye ukuhlolwa okwenziwe ngabaphenyi abafanayo, ababambiqhaza abanokwesaba izindawo eziphakeme bathola i-placebo noma i-200 mg GABA (ngesimo sePharmaGABA) ngaphambi kokuwela ibhuloho lokumiswa ngaphezu komhosha. Amazinga amathe we-antibody immunoglobulin-A (sIgA) —okuhlotshaniswa nokuphumula emazingeni aphezulu — alinganiswa ngezigaba ezahlukahlukene. Iqembu le-placebo lithole ukwehla okukhulu kwe-sIgA, ngenkathi amazinga eqembu le-GABA ahlala ezinzile futhi anyuka kancane ekugcineni, okukhombisa ukuthi bahlala bekhululekile ngokwengeziwe.

 

I-GABA nokugxila kwengqondo

Ucwaningo lukhombisa ukuthi i-GABA ingaba nethonya elihle emandleni omuntu wokwenza imisebenzi yengqondo edinga ukuhlushwa okukhulu futhi aqede ukukhathala okungokwengqondo nokungokomzimba okulimaza lokhu kuhlushwa.

Kwesinye isifundo esincane, ababambiqhaza (abaningana babo ababekhathala okungapheli) banikezwa isiphuzo esiqukethe u-0, 25, noma u-50 mg we-GABA base becelwa ukuthi benze inkinga enzima yezibalo. Abaphenyi bathola ukuthi labo abasemaqenjini amabili e-GABA babone ukwehla okukhulu ekukhathaleni ngokwengqondo nangokomzimba, njengoba kulinganiswa ukwehliswa kwama-biomarker athile kubandakanya i-cortisol. * Labo abaseqenjini lama-50-mg nabo bathola amaphuzu aphezulu kunkinga yezibalo, bephakamisa ukugxila okuthuthukile nenkinga ikhono lokuxazulula.

 

I-GABA yengcindezi yegazi enempilo

Ucwaningo lokuqala lubonisa ukuthi i-GABA ingakhuthaza umfutho wegazi onempilo, okungenani ngokwezifundo ezimbalwa zelebhu. Kucatshangwa ukuthi i-GABA kungenzeka isebenza ngokusiza imithambo yegazi ukuba ikhule kangcono, ngaleyo ndlela ithuthukise umfutho wegazi onempilo.

Ukuqonda ukuthi i-GABA ingasebenza kanjani ekusekeleni ukucindezelwa kwegazi okunempilo kuzodinga ucwaningo olunamandla, kepha isifundo esisodwa sokuqala sathola ukuthi ukwengezelwa nsuku zonke nge-80 mg ye-GABA kube nomthelela omuhle ekucindezelweni kwegazi kubantu abadala.

 

IGamma-aminobutyric acid kusebenzisa?

I-Gamma-aminobutyric acid — evame ukubizwa ngokuthi yi-GABA — iyi-amino acid ne-neurotransmitter, uhlobo lwamakhemikhali olubhekele ukuthwala imininingwane isuke kwesinye iseli iye kwesinye.

Ikhiqizwe ngokwemvelo emzimbeni, i-GABA nayo iyatholakala kabanzi kwifomu lokungezelela. Abakhiqizi bathi izengezo ze-GABA zingasiza ukukhuphula amazinga e-GABA obuchopho kanye nokwelapha ukukhathazeka, ingcindezi, ingcindezi nezinkinga zokulala. Eqinisweni, abanye abakhiqizi bezengezo babiza i-GABA ngokuthi “uhlobo lwemvelo lweValium” —okusho ukuthi kunciphisa ukucindezeleka futhi ithuthukise ukuphumula nokulala.

Ucwaningo lukhombisa ukuthi i-GABA ingadlala indima enkulu ekuvikeleni ukudana nokukhathazeka. Isibonelo, ucwaningo olushicilelwe ku-Journal of Biological Chemistry ngo-2010 lubonisa ukuthi abantu abanokucindezeleka okukhulu bangaba namazinga aphansi e-GABA. Le miphumela iyahambisana neqiniso lokuthi i-GABA yi-neurotransmitter yokutholisa eyinhloko ebuchosheni.

 

isilinganiso

I-GABA ithathwa ngomlomo ekudambiseni ukukhathazeka, ukuthuthukisa imizwa, ukunciphisa izimpawu ze-premenstrual syndrome (PMS), kanye nokwelashwa kokushoda-i-hyperactivity disorder (ADHD). Iphinde isetshenziselwe ukukhuthaza ukukhula kwemisipha emile, ukushisa amafutha, ukuzinzisa ukucindezelwa kwegazi nokuqeda izinhlungu.

Ngoba kunolwazi olunqunyelwe mayelana nezengezo ze-GABA, awukho umthamo onconywayo uma ukhetha ukwengeza.

Ekuvivinyweni komtholampilo, imithamo ehlukahlukene yezengezo ze-GABA isetshenzisiwe. Isibonelo, i-100 mL yobisi oluvutshiwe oluqukethe i-10-12 mg ye-GABA nge-100 mL isetshenziswe yiziguli ezinomfutho wegazi ophakeme esifundweni lapho beziphuza khona nsuku zonke ngesidlo sasekuseni amaviki ayi-12. Kwesinye isifundo, isithasiselo se-chlorella esiqukethe ama-20 mg we-GABA sithathwe kabili nsuku zonke amasonto ayi-12.

 

Gaba powder ukudayiswa(Ungathenga kuphi i-GABA powder ngobuningi)

Inkampani yethu ithokozela ubudlelwane besikhathi eside namakhasimende ethu ngoba sigxile ekusebenzeni kwamakhasimende nokunikezela ngemikhiqizo emihle. Uma unentshisekelo ngomkhiqizo wethu, siyavumelana nezimo nge-oda eyenziwe ngokwezifiso ukuze ivumelane nesidingo sakho esithile nesikhathi sethu sokuhola esisheshayo kuma-oda siqinisekisa ukuthi uzowunambitha kakhulu umkhiqizo wethu ngesikhathi. Siphinde sigxile nezinsizakalo ezingezwe zenani. Sitholakala ngemibuzo yensiza nolwazi lokuxhasa ibhizinisi lakho.

Singumhlinzeki we-GABA powder oqeqeshiwe iminyaka eminingana, sinikezela ngemikhiqizo ngentengo yokuncintisana, futhi umkhiqizo wethu ungowekhwalithi ephezulu kakhulu futhi uhlolwa ngokuqinile, nokuzimela ukuqinisekisa ukuthi kuphephile ukusetshenziswa emhlabeni jikelele.

 

Okubhekwayo

[1] UHaynes, uWilliam M., ed. (2016). I-CRC Handbook yeKhemistry kanye nePhysics (97th ed.). Cindezela i-CRC. amakhasi 5-88. I-ISBN 978-1498754286.

[2] WG Van der Kloot; J. Robbins (1959). "Imiphumela ye-GABA ne-picrotoxin kumandla okuhlangana kanye nokusikwa kwemisipha ye-crayfish". Isipiliyoni. 15:36.

[3] URoth RJ, Cooper JR, Bloom FE (2003). Isisekelo Se-Biochemical of Neuropharmacology. I-Oxford [Oxfordshire]: I-Oxford University Press. k. 106. I-ISBN 978-0-19-514008-8.

 


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