Umkhiqizi 7,8-DIHYDROXYFLAVONE | I-Tropoflavin - i-Cofttek

I-7,8-Dihydroxyflavone powder

November 23, 2021

I-Cofttek ingumkhiqizi wempushana we-7,8-DIHYDROXYFLAVONE ongcono kakhulu e-China. Imboni yethu inohlelo oluphelele lokuphatha ukukhiqiza (ISO9001 & ISO14001), olunamandla okukhiqiza anyanga zonke angama-260kg.


Isimo: Ekukhiqizeni kweMisa
Iyunithi: 1kg / isikhwama, 25kg / Drum

Siziqu

Igama: 7,8-DIHYDROXYFLAVONE
CAS: 38183-03-8
Ukuhlanzeka 98%
Ifomula Yamamolekhula: C15H10O4
Isisindo Yamamolekhula: I-254.238 g / mol
I-Melt Point: I-250-252 ° C
Igama lamakhemikhali: I-Tropoflavin; 7,8-DHF
omqondofana: 7,8-dihydroxyflavone 38183-03-8 7,8-dihydroxy-2-phenyl-4H-chromen-4-one 7,8-Dihydroxyflavone hydrate 7,8-DHF
InChI Key: COCYGNDCWFKTMF-UHFFFAOYSA-N
Ukuphila okungaphelele: < 30 imizuzu (kumagundane)
Umswakama: I-7,8-DHF iyancibilika kuzincibilikisi zemvelo ezifana ne-ethanol, i-DMSO, ne-dimethyl formamide (DMF).
Isimo Sokugcina: 0 - 4 C isikhathi esifushane (izinsuku kuya emavikini), noma -20 C isikhathi eside (izinyanga)
Isicelo: I-7,8-DHF iyi-flavonoid yokwenziwa engafinyelela ebuchosheni futhi isebenze i-receptor (TrkB) ekhuthaza ukukhula kwe-neuronal. Obunye ubufakazi bezilwane bubonisa ukuthi i-7,8-DHF ingase ibe nezinzuzo ezithile zokuqonda kanye nemoto futhi ingase ibe nootropic.
ukubukeka: Iphuphu eliphuzi

 

Iyini i-7,8-DIHYDROXYFLAVONE (38183-03-8)?

I-7,8-Dihydroxyflavone (7,8-DHF) iyiflavone etholakala ezitshalweni. Kutholwe ngesikhathi kuseshwa ama-molecule alingisa umsebenzi we-brain-derived neurotrophic factor (BDNF).

I-BDNF ikhuthaza ukukhula kwama-neurons nama-synapses (synaptogenesis) futhi ibaluleke kakhulu ekusebenzeni kobuchopho okuvamile. Amanani aphansi e-BDNF abonwa ezifweni ezinjengokucindezeleka, i-Alzheimer's, i-Parkinson's, ne-schizophrenia.

Ucwaningo ezilwaneni lubonisa ukuthi i-7,8-DHF ingasiza ekulungiseni ubuchopho, inkumbulo yesikhathi eside, ukucindezeleka, kanye nezifo ze-neurodegenerative.

 

7,8-DIHYDROXYFLAVONE (38183-03-8) izinzuzo

Imemori nokuFunda

I-7,8-DHF ithuthukise ukuqashelwa kwento (ukuhlolwa okusetshenziselwa ukunquma ukufunda nenkumbulo) kumagundane anempilo lapho enikezwa ngokushesha ngemva namahora amathathu ngemva kokufunda. Kuphinde kwathuthukisa inkumbulo kumagundane anokuwohloka komqondo. Kumamodeli wamagundane we-post-traumatic stress disorder (PTSD), i-7,8-DHF ivimbele ukukhubazeka kwenkumbulo okuhlobene nokucindezeleka. I-7,8-DHF iphinde yathuthukisa inkumbulo kumagundane aguga.

 

Ukulungisa Ubuchopho

I-7,8-DHF ikhuthaze ukulungiswa kwezinzwa ezilimele. Iphinde yandisa ukukhiqizwa kwama-neuron amasha ebuchosheni bamagundane amadala ngemva kokulimala kobuchopho futhi yakhuthaza ukukhula kwe-neuron kumagundane asebekhulile. Ngokufanayo, i-7,8-DHF, kanye nokuzivocavoca, ngcono ukusebenza kobuchopho kumagundane athola ukulimala kwengqondo okubuhlungu.

 

Izifo ze-Alzheimer

Kumamodeli ezilwane zesifo i-Alzheimer's, 7,8-DHF:

Ukwakhiwa kwe-amyloid plaque encishisiwe

Ukucindezeleka okwenziwe nge-oxidative

Kuvinjelwe ukulahleka kwama-synapses

Kugwenywe ukushoda kwenkumbulo futhi kugcinwe ukusebenza kwengqondo

Nokho, olunye ucwaningo alutholanga zinzuzo ekwelapheni amagundane ngokulimala kwengqondo okufana ne-Alzheimer's nge-7,8-DHF.

 

Isifo sikaParkinson

I-7,8-DHF ithuthukise ukusebenza kwemoto futhi ivimbele ukulahleka kwama-neurons ahlobene ne-dopamine kumodeli yegundane lesifo sika-Parkinson.

Kuphinde kuvimbele ukufa kwama-neurons azwela i-dopamine kumamodeli wezinkawu zesifo sika-Parkinson.

 

7,8-DIHYDROXYFLAVONE (38183-03-8) kusebenzisa?

I-7,8-Dihydroxyflavone (7,8-DHF) iyi-flavonoid eyenzeka ngokwemvelo. Ibonise ukusebenza ngempumelelo ngokumelene nezifo eziningana zesistimu yezinzwa, kuhlanganise ne-Alzheimer's, Parkinson's, ne-Huntington's. I-7,8-Dihydroxyflavone (7,8-DHF) kucatshangwa ukuthi iyi-ejenti ethembisayo yokwelapha izifo ezihlukahlukene ze-neurodegenerative.

 

7,8-DIHYDROXYFLAVONE (38183-03-8) isilinganiso

I-7,8-DHF ingathengwa njengamaphilisi/amaphilisi, noma impushana.

Awukho umthamo ophephile nosebenzayo we-7,8-DHF ngoba alukho ucwaningo olunamandla anele olwenziwa ukuze kutholwe eyodwa. Umthamo ovame kakhulu ezithanjeni ezitholakalayo ezithengiswayo ngu-10 - 30 mg ngosuku.

 

7,8-DIHYDROXYFLAVONE powder ukudayiswa(Uthenga kuphi i-7,8-DIHYDROXYFLAVONE powder ngobuningi)

Inkampani yethu ithokozela ubudlelwane besikhathi eside namakhasimende ethu ngoba sigxile ekusebenzeni kwamakhasimende nokunikezela ngemikhiqizo emihle. Uma unentshisekelo ngomkhiqizo wethu, siyavumelana nezimo nge-oda eyenziwe ngokwezifiso ukuze ivumelane nesidingo sakho esithile nesikhathi sethu sokuhola esisheshayo kuma-oda siqinisekisa ukuthi uzowunambitha kakhulu umkhiqizo wethu ngesikhathi. Siphinde sigxile nezinsizakalo ezingezwe zenani. Sitholakala ngemibuzo yensiza nolwazi lokuxhasa ibhizinisi lakho.

Singabahlinzeki bempushana be-7,8-DIHYDROXYFLAVONE iminyaka eminingana, sihlinzeka ngemikhiqizo ngentengo yokuncintisana, futhi umkhiqizo wethu usezingeni eliphezulu kakhulu futhi uhlolwa okuqinile, okuzimele ukuze siqinisekise ukuthi uphephile ukusetshenziswa emhlabeni jikelele.

 

Okubhekwayo

  1. Schliebs R, Arendt T (2006) Ukubaluleka kwesistimu ye-cholinergic ebuchosheni ngesikhathi sokuguga kanye nesifo i-Alzheimer's. J Neural Transm (Vienna) 113:1625–1644.
  2. Corbett A, Ballard C (2012) Imithi emisha nesafufusa yesifo i-Alzheimer's. I-Expert Opin Emerg Izidakamizwa 17:147–156.
  3. Giacobini E, Gold G (2013) Ukwelashwa kwesifo i-Alzheimer: Ukusuka ku-amyloid-β kuya e-tau. Nat Rev Neurol 9:677-686.
  4. I-Zuccato C, i-Cattaneo E (2009) I-neurotrophic factor etholakala ebuchosheni ezifweni ze-neurodeergenerative. Nat Rev Neurol 5:311–322.

 


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