I-Coluracetam ehamba phambili (135463-81-9) Umkhiqizi - iCofttek

IColuracetam (135463-81-9)

Kwangathi 8, 2021

ICofttek ingumkhiqizi we-Coluracetam powder omuhle kakhulu e-China. Ifektri yethu inohlelo oluphelele lokuphathwa kokukhiqiza (i-ISO9001 & ISO14001), enomthamo wokukhiqiza wanyanga zonke we-160kg.

 


Isimo: Ekukhiqizeni kweMisa
Iyunithi: 1kg / isikhwama, 25kg / Drum

IColuracetam (135463-81-9) Siziqu

Igama: I-Coluracetam
CAS: 135463-81-9
Ukuhlanzeka 98%
Ifomula Yamamolekhula: C19H23N3O3
Isisindo Yamamolekhula: 341.411 g / moll
I-Melt Point: N / A
Igama lamakhemikhali: N-(2,3-dimethyl-5,6,7,8-tetrahydrofuro[2,3-b]quinolin-4-yl)-2-(2-oxopyrrolidin-1-yl)acetamide

I-MKC-231

bci-540

omqondofana: I-Coluracetam; BCI-540; I-MKC-231; BCI 540; MKC 231; BCI540; MKC231.
InChI Key: I-PSPGQHXMUKWNDI-UHFFFAOYSA-N
Ukuphila okungaphelele: N / A
Umswakama: I-Soluble ku-DMSO
Isimo Sokugcina: Okomile, okumnyama naku-0 - 4 C isikhathi esifushane (izinsuku kuya emasontweni) noma -20 C isikhathi eside (izinyanga kuya eminyakeni)
Isicelo: I-Raw Coluracetam powder (MKC-231) yisisetshenziswa somuthi we-racetam okuthiwa yi-como nootropic.
ukubukeka: i-powder emhlophe i-white

 

IColuracetam (135463-81-9) I-NMR Spectrum

IColuracetam (135463-81-9) I-NMR Spectrum

Uma udinga i-COA, i-MSDS, i-HNMR yeqoqwana ngalinye lomkhiqizo nolunye ulwazi, sicela uxhumane nathi umphathi wezentengiso.

 

Kuyini I-Coluracetam (135463-81-9)?

I-Raw Coluracetam powder (MKC-231) yisisetshenziswa somuthi we-racetam okuthiwa yi-como nootropic. Ayinayo ubufakazi obuningi bokufaka uphenyo, kepha izindlela zokusebenza (kanye nokuhleleka) zibonakala zihluke kakhulu kwezinye izinhlanganisela ze-racetam njengePiracetam noma i-Aniracetam.

I-Raw Coluracetam powder ibonakala isebenzisana nenqubo eyaziwa ngokuthi i-HACU emfushane kakhulu (i-HACU okwesikhashana), okuyinto isinyathelo sokulinganisa isilinganiso sokudweba se-neuron ukuze kufakwe phakathi kwe-neurotransmitter acetylcholine. Ukwandisa isilinganiso se-HACU kubonakala kukwandisa umsebenzi we-nelinon cholinergic, ngakho-ke kuyisisindo esifunyiwe sokuthuthukiswa kwengqondo.

 

I-Coluracetam (135463-81-9) izinzuzo

  • Thuthukisa Inkumbulo Nokufunda
  • Thuthukisa Ukuqondisisa Ukufundwa Kakhulu nokukhumbula Okukhululekile
  • Ukuthuthukiswa Kokuqonda Kwesikhathi Eside
  • Yehlisa Ukwelapha-Ukumelana Nokudangala
  • Ukuphakanyiswa okungenzeka kweNeurogene
  • Ingathuthukisa ukukhubazeka kwengqondo
  • Kwangathi Ungathuthukisa Umbono
  • Ukuthuthuka kwesibonakaliso se-Angryable Bowel Syndrome
  • Ukusetshenziswa kokuzijabulisa kwe-Coluracetam

 

I-Coluracetam (135463-81-9) kusebenzisa

IColuracetam (INN) (igama lekhodi i-BCI-540; phambilini i-MKC-231) i-powder iyi-ejenti ye-nootropic yomndeni we-racetam. Ekuqaleni yathuthukiswa futhi yahlolwa yiMitsubishi Tanabe Pharma Corporation yesifo i-Alzheimer's. Ngemuva kokuthi lesi sidakamizwa sehlulekile ukufinyelela emaphethelweni esivivinyweni saso somtholampilo sabe sesinikezwe ilayisense yiBrainCells Inc yophenyo ngesifo esikhulu sokucindezeleka (MDD), esandulelwa ngokunikezwa i- “Qualifying Therapeutic Discovery Program Grant” ngumbuso waseCalifornia.

 

I-Coluracetam (135463-81-9) Isikali

Iningi locwaningo olwenziwe nge-coluracetam lwenziwa ezilwaneni kunabantu, ngakho-ke awekho imihlahlandlela yokulandelwa kwemvelo eyamukelekile emhlabeni wonke. Ibanga le-dosage elisebenzayo lichazwe ngokujwayelekile njenge-5-20 mg. Abasebenzisi be-coluracetam baye babika amanani amaningi ahlukahlukene alawulwa ngomlomo nangezingqikithi.

Impendulo yomsebenzisi iphinde isho ukuthi ukubekezelelana kwe-coluracetam powder kungakhula ngokushesha. Njengayo yonke imishanguzo, ikakhulukazi ama-nootropics, kungcono ukuqala ngamanani amancane bese ukhuphula umthamo kancane kancane njengoba umzimba wakho uphendula futhi ulungisa umuthi. IColuracetam ayinabuthi futhi ibhekwa njengokubekezelela kahle futhi ephephile.

 

I-Coluracetam powder ukudayiswa(Ungathenga kuphi i-Coluracetam powder ngobuningi)

Inkampani yethu ithokozela ubudlelwane besikhathi eside namakhasimende ethu ngoba sigxile ekusebenzeni kwamakhasimende nokunikezela ngemikhiqizo emihle. Uma unentshisekelo ngomkhiqizo wethu, siyavumelana nezimo nge-oda eyenziwe ngokwezifiso ukuze ivumelane nesidingo sakho esithile nesikhathi sethu sokuhola esisheshayo kuma-oda siqinisekisa ukuthi uzowunambitha kakhulu umkhiqizo wethu ngesikhathi. Siphinde sigxile nezinsizakalo ezingezwe zenani. Sitholakala ngemibuzo yensiza nolwazi lokuxhasa ibhizinisi lakho.

Singumhlinzeki we-powder oyi-Coluracetam okweminyaka eminingana, sihlinzeka ngemikhiqizo ngamanani aphansi, futhi umkhiqizo wethu ungowekhwalithi ephezulu kakhulu futhi uhlolwa ngokuqinile, nokuzimela ukuqinisekisa ukuthi kuphephile ukusetshenziswa emhlabeni wonke.

 

Okubhekwayo

[1] Akaike A, et al. (1998). Umphumela wokuvikela we-MKC-231, inoveli ephezulu yokuthola i-choline ethola isithuthukisi, kwi-glutamate cytotoxicity kuma-cortical neurons akhulisiwe. I-Jpn J Pharmacol.

[2] UBessho, T., Takashina, K., Tabata, R., Ohshima, C., Chaki, H., Yamabe, H., Egawa, M., Tobe, A., & Saito, K. (1996). Umphumela wenoveli yokuhlangana okuphezulu kwe-choline ethola isithuthukisi 2- (2-oxopyrrolidin-1-yl) -N- (2,3-dimethyl-5,6,7,8-tetrahydrofuro [2,3-b] quinolin-4- yl) i-acetoamide ekushodeni kwemethingi yamanzi yokufunda kumagundane. I-Arzneimittel-Forschung, 46 (4), 369-373.

[3] UMurai, S., Saito, H., Abe, E., Masuda, Y., Odashima, J., & Itoh, T. (1994). I-MKC-231, isithuthukisi sokutholwa kwe-choline, ivuselela ukusilela kwenkumbulo yokusebenza futhi yehlise i-hippocampal acetylcholine ebangelwa yi-ethylcholine aziridinium ion kumagundane. Ijenali yokuThuthwa kweNeural, 98 (1), 1–13 / bf10.1007.

[4] UTakashina K, uBessho T, uMori R, u-Eguchi J, uSaito K. MKC-231, isithuthukisi se-choline: (2) Umthelela ekwakhiweni nasekukhishweni kwama-acetylcholine kumagundane aphathwe yi-AF64A. J Neural Transm (Vienna). 2008 Jul; 115 (7): 1027-35. doi: 10.1007 / s00702-008-0048-1. I-PubMed PMID: 18446264.

[5] IShirayama Y, Yamamoto A, Nishimura T, Katayama S, Kawahara R. Ukuchayeka okulandelayo kwesithako sokuqina se-choline kuqinisa i-MKC-231 iphikisana nokushiyeka kokuziphatha kokunciphiswa kwe-phencyclidine kanye nokuncishiswa kwama-septal cholinergic neurons kumagundane. I-Eur Neuropsychopharmacol. 2007 Sep; 17 (9): 616-26. I-PubMed PMID: 17467960.