UHAMBO LOKUHLOLA ICEBO

UMBONO WAMAHHALA WOKUGCINA

IMISEBENZI YAMAHHALA NEZIFO

Imvamisa, ama-radicals amahhala ayadingeka emizimbeni, kepha ama-radicals wamahhala ngokweqile angadala ukungalingani kokusebenza komzimba, bese kuholela ekucindezelekeni kwe-oxidative okuvela ezifweni ezahlukahlukene (imibhalo ekhombisa ukuthi ama-radicals amahhala angumthombo wezifo ezahlukahlukene).

I-ANTIOXIDANT

Imizimba yethu ayikwazi ukusebenza ngaphandle komoya-mpilo, futhi uma inani elikhulu lama-radicals amahhala lenyuka, umzimba ongaphansi kwengcindezi ye-oxidative uzokwenza ukuthi uhlelo lokulungisa lwehluleke ekususeni ama-radicals wamahhala ngokweqile. Ezimweni ezikhethekile, umzimba udinga ukugcwalisa ama-antioxidants in vitro ukususa ama-radicals wamahhala ngokweqile.

UKUTHUTHUKISWA KWAMA-ANTIOXIDANTS

L-I-ERGOTHIONEINE -UHLOBO OLUSHA LWE-ANTioxidant Yemvelo

ISIQINISEKISO

Ngezinzuzo zemisebenzi eminingi, Umhl ivelele phakathi kwamanye ama-antioxidants amaningi.

UBUHLE

Ukuqhathaniswa KOKUFANYELELA

Ezenye: Umhl ibingumdwebi osebenza kakhulu wama-radicals wamahhala uma kuqhathaniswa nama-antioxidants akudala njenge-GSH, i-uric acid ne-trolox. Ikakhulu, umthamo ophakeme kakhulu we-antioxidant okhonjiswe yi-EGT vs. peroxyl radicals uholele ngama-25% aphezulu kunenani elitholwe ngereferensi antioxidant trolox. Umthamo wokukhwabanisa we-EGT maqondana ne-hydroxyl radicals wawungaphezulu ngama-60%, uma kuqhathaniswa ne-uric acid, emele ireferensi antioxidant vs. hydroxyl radicals. Ekugcineni, i-EGT ikhombise umsebenzi ophakeme kakhulu we-antioxidant futhi maqondana ne-peroxynitrite, enekhono lokukhwabanisa elingu-10% ngaphezulu kunele-uric acid.

EMINYE IMISEBENZI

I-EGT inemiphumela kulawulo lwamandla we-intracellular,

kuthuthukisa ukungatheleleki,

ukwenza ngcono isilinganiso sokusinda kwesidoda,

ukuvikela isibindi ekulimaleni,

ukuvimbela ukuvuvukala,

i-neurodegeneration,

iziphazamiso zokuthuthuka nokukhubazeka.

UKUDINGEKA KWENTUTHUKO

① AMAHLA ATHOLWE NGOKUBANZI KWEZIMBALI NEZILWANE

② IMIYALELO

I-5-10mg iyunithi ngayinye yomuntu omdala kanye nama-2-3 amayunithi wokudla okuqhubekayo kubalulekile ekudleni kwakho kwansuku zonke.

Umthombo: Li Yiqun, Zhou Nianbo. Imisebenzi Yebhayoloji kanye Nezicelo ze-EGT [J]. Ubunjiniyela Bokudla, 2010 9 （3） ： 26-28.

Ukufakwa kuhlu kubhalwe kanjena:

Izingane (iminyaka emi-3 kuya kwe-11)	≤l 0 mg / usuku
Ubusha (iminyaka eyi-11-21）	≤30 mg / usuku
Abantu abadala (iminyaka engama-21-80)	≤30 mg / usuku
Qaphela:1. Imithamo yezingane kanye nabantu abadala (iminyaka engu-3 -80 ubudala) 2.Ukusetshenziswa kwabesifazane abakhulelwe noma abancelisayo akunconywa.

Umthombo wedatha: I-Tetrahedron lapho ufaka isicelo se-US NDI

Imininingwane iphakamisa: 10.5mg / g ye-OXIS's ADI (Ukwamukelwa Kwansuku Zonke Okumukelekile).

③ ISYNTHESIS

UKWANDISWA NOKUSETSHENZISWA

(1) ISIQEPHU

Njengamanje, kunezindlela ezintathu zokukhiqizwa kwe-EGT: synthesis synthesis, zemvelo ukukhishwa kwe-bio (ikakhulukazi kusuka kumakhowe, izicubu zezilwane nokukhishwa kwegazi), kanye nendlela ye-biosynthesis.

Ukuqhathanisa Izindlela Zokukhipha EGT

(2) ISICELO

I-EGT inezicelo ezibanzi kuzimonyo, ukudla okusebenzayo, imithi yokwelapha, imithi yokwelapha, i-biomedicine, njalonjalo.

(3) EZINYE IZICELO EZIKHONA

Okubhekwayo

1. I-Oleoylethanolamide (oea) –i-wand yemilingo yempilo yakho
2. I-Anandamide vs cbd: yikuphi okungcono empilweni yakho? Konke odinga ukukwazi ngabo!
3. Konke odinga ukukwazi mayelana ne-nicotinamide riboside chloride
4. Izithasiselo ze-Magnesium l-threonate: izinzuzo, isilinganiso, nemiphumela emibi
5. I-Palmitoylethanolamide (ipea): izinzuzo, isilinganiso, ukusetshenziswa, ukwengeza
6. Izinzuzo eziphezulu zezempilo eziyi-6 zezengezo ze-resveratrol
7. Izinzuzo ezi-5 eziphezulu zokuthatha i-phosphatidylserine (ps)
8. Izinzuzo ezi-5 eziphezulu zokuthatha i-pyrroloquinoline quinone (pqq)
9. Isengezo esihle kakhulu se-alpha gpc
10. Isengezo esihle kakhulu sokulwa nokuguga se-nicotinamide mononucleotide (nmn)