Ukubonisa 1-12 of 22 imiphumela

I-CAS CHA. I-PRODUCT NAME ISENDLALELO
    934162-61-5 A-966492 (934162-61-5)

    I-966492 iyi-inhibitor enomlando futhi enamandla ka-PARP1 no-PARP2 ne-Ki ka-1 nM ne-1.5 nM, ngokulandelana.

    328543-09-5 I-AG14361 (328543-09-5)

    I-AG14361 iyinhlangano ye-PARP-1 enamandla ye-PARP-5, ne-Ki ye-<620 nM, naku-permeabilized SW620 namaseli we-SW50 aqondile, i-IC29 yi-14 nM ne-XNUMX n ...

    1645286-75-4 I-AZ6102 (1645286-75-4)

    I-AZ6102 yi-TNKS1 / 2 inhibitor enamandla kakhulu (IC50 = 3 / 1 nM) ene-100 ngokukhetha ngokumelene namanye ama-enzyme omndeni we-PARP (IC50: 0.5-3 μM) futhi ibonisa ...

    1174043-16-3 I-AZD2461 (1174043-16-3)

    I-AZD2461 iyinhlangano ye-PARP inhibitor inoveli futhi enamandla ne-IC50 ye-5 nM, i-2 nM ne-200 nM ye-PARP1, PARP2 ne-PARP3, ngokulandelanayo. Ubuhlobo bayo obuphansi ...

    66611-37-8 I-BGP-15 (66611-37-8)

    I-BGP-15 iyinhlangano ye-polymerase ye-polymerase ye-poly (i-ADP-ribose) inoveli inoveli, enezindima ku-DNA ukulungiswa kanye ne-apoptosis ...

    1207456-01-6 I-BMN673 (1207456-01-6)

    I-BMN 673 iyinhlangano ye-PARP inhibitor ne-IC50 ye-0.58 nM. Ibuye inhibitor enamandla ka-PARP-2, kodwa ayivimbeli i-PARG futhi inomuzwa kakhulu ...

    868540-17-4 I-Carfilzomib (i-PR171) (868540-17-4)

    I-Carfilzomib (i-PR171) i-proteasome inhibitor engenakuphikiswa kanye ne-antinoplastic agent esetshenziselwa ekwelapheni i-myeloma eminingi engamanga ....

    134381-21-8 I-Epoxomicin (134381-21-8)

    I-Epoxomicin i-proteasome i-proteasome inhibitor enomsebenzi wokulwa nokuvuvukala, ivimbela ngokuyinhloko umsebenzi we-CH-L we-proteasome ye-20S, i ...

    415903-37-6 I-Grapiprant (415903-37-6)

    Umqashi, owaziwa nangokuthi i-AT-001 no-CJ-023, uyisidakamizwa esivela ekilasini lesiphathimandla. Lezi zinhlayiya zazivela ku-acylsulfonamide futhi ziyi-char ...

    133407-82-6 I-MG132 (133407-82-6)

    I-MG132 iyi-proteasome ne-calpain inhibitor enamandla kakhulu ye-proteasome ne-calpain ene-IC50 ye-0.1 ne-1.2 μM yokuvimbela i-proteasome ne-calpain, ...

    1038915-60-4 I-MK4827 (i-Niraparib) (1038915-60-4)

    I-MK-4827 (i-Niraparib) iyinhibitha yokukhetha ye-PARP1 / PARP2 ne-IC50 ye-3.8 nM / 2.1 nM; ngemisebenzi emikhulu emangqamuzaneni omdlavuza we-BRCA-1 we-mutant ...

    489402-47-3 I-ML213 (489402-47-3)

    I-ML213 yi-activator ekhethiwe yeziteshi ze-Kv7.2 ne-Kv7.4, ithuthukisa iziteshi ze-Kv7.2 ne-Kv7.4 nama-EC50 we-230 no-510 nM, ngokulandelana.

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