Ukubonisa yonke 11 imiphumela

I-CAS CHA. I-PRODUCT NAME ISENDLALELO
    1668553-26-1 A-1210477 (1668553-26-1)

    I-A-1210477 iyinhlangano enamandla futhi ikhetha i-MCL-1 inhibitor nge-Ki ne-IC50 ye-0.454 nM ne-26.2 nM, ngokulandelana,> ukukhetha kwe-100 ngokunye ...

    1426138-42-2 I-FX1 (1426138-42-2)

    I-FX1 yi-BCL6 inhibitor enamandla futhi eqondile, ene-IC50 ye-35 μM.FX1 engumgogodla we-B cell lymphoma 6 (BCL6). ....

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    803647-40-7 I-NSC59984 (803647-40-7)

    I-NSC59984 yenza inqubo ye-p53 yokuguqulwa kwamaprotheni nge-MDM2 nomgwaqo we-ubiquitin-proteasome. I-EC50 ye-NSC59984 kuningi lamaseli omdlavuza ...

    1313363-54-0 I-NVP-CGM097 (1313363-54-0)

    I-NVP-CGM097 (CGM-097) iyinhlangano ye-MDM2 enamandla futhi ekhethiwe; i-anti-biovailable ye-HDM2 ephikisana nomsebenzi onamandla we-antineoplastic & #

    803712-79-0 I-Mesatlate ye-Obatoclax (GX15-070) (803712-79-0)

    I-Obatoclax Mesylate (i-GX15-070) ingumphikisi we-Bcl-2 ne-Ki ka-0.22 μM kusivivinyo samahhala, angasiza ekunqobeni isamba esiphelelwane se-MCL-1 ...

    939981-39-2 I-RG7112 (939981-39-2)

    I-RG7112 iyi-molecule encane emtholampilo encane ye-MDM2 inhibitor eyenzelwe ukuphatha iphakethe le-P53-binding ye-MDM2 ....

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    1229705-06-9 I-RG7388 (1229705-06-9)

    I-RG7388 iyinhlangano ephikisanayo yomlomo, ekhethiwe, encane ye-MDM2 evimbela ukubopha kwe-MDM2 ku-p53. I-Idasanutlin, eyaziwa nangokuthi i-RG7388 ne-RO55 ...

    1309684-94-3 RO8994 (1309684-94-3)

    I-RO8994 iyichungechunge elinamandla kakhulu lokukhetha i-spiroindolinone encane-molecule ye-MDM2 inhibitor, ne-IC50 ye-5 nM (i-HTRF yokulinganisa ukuhlolwa) kanye ...

    1262888-28-7 I-Spautin-1 (1262888-28-7)

    I-Spautin-1 iyi-inhibitor ye-autophagy inoveli, i-IM ivimbele ukukhula kwamaseli we-K562 ne-IC50 ye-1.03 μM. Ngokuphambene, ukubambisana ...

    1011301-27-1 I-Tenovin-3 (1011301-27-1)

    I-Tenovin-3 iyakwazi ukwandisa amazinga we-P53, anqunywe kumaseli we-MCF-7 aphathwe nge-6hr ku-10 μM.Tenovin-3 ngumsunguli we-P53 kanye nomvimbela we ...

    1431866-33-9 WEHI539 (1431866-33-9)

    I-WEHI-539, inokubambisana okuphezulu (subnanomolar) nokukhethwa kwe-BCL-XL futhi ibulala ngamangqamuzana ngamaseli ngokukhetha ngokumelene nokuphikisana kwayo ...