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Ukubonisa yonke 12 imiphumela

I-CAS CHA. I-PRODUCT NAME ISENDLALELO
    1146699-66-2 I-Avagacestat (1146699-66-2)

    I-Avagacestat (i-BMS-708163) iyinhlangano ye-γ-secretase i-γ-secretase inhibitor ye-Aβ40 ne-Aβ42 ene-IC50 ye-0.3 nM ne-0.27 nM, ...

    208255-80-5 I-DAPT (GSI-IX) (208255-80-5)

    I-DAPT (i-GSI-IX) iyinhibithi ye-γ-secretase inhibitor, evimbela ukukhiqizwa kwe-Aβ ne-IC50 ye-20 nM kuma-HEK 293 amaseli.

    1446502-11-9 I-Enasidenib (1446502-11-9)

    I-Enasidenib iyinkulumo enamandla, ekhethiwe, eguquguqukayo yokuguqula i-IDH2. I-Enasidenib, i-aslo eyaziwa ngokuthi i-AG-221 ne-CC-90007, iyinhlangano enamandla futhi enamandla ...

    313967-18-9 I-FLI-06 (313967-18-9)

    I-FLI-06 iyi-inhibitor yesinoveli yokukhomba kwe-Notch nge-EC50 ye-2.3 μM. I-FLI-06 iyi-inhibitor ye-Notch kanye ne-inhibitor yangaphambili ye-secretory pathway. I-FL ...

    147591-46-6 ID8 (147591-46-6)

    I-ID-8 i-DYRK inhibitor, futhi isekela umbryonic stem cell ukuzivuselela ngokwesiko lesikhathi eside. I-ID-8 i-DYRK inhibitor. I-ID-8 ingase isekele i-Wn ...

    459168-41-3 I-JNJ7777120 (459168-41-3)

    I-JNJ-7777120 iyinhlangano yokuqala ye-anti-imidazole engenamimidazole ye-H4 ne-Ki ye-4.5 nM, imibukiso> 1000-phinda ukhethe ...

    668467-91-2 I-LDN-57444 (668467-91-2)

    I-LDN-57444 i-inhibitor yokuvuselela i-proteasome inhibitor ye-Uch-L1 ne-IC50 ye-0.88 μM, ukukhethwa kwe-28 ngokulandelana kwe-isoform Uch-L3.

    ...

    603139-19-1 I-Odanacatib (MK-0822) (603139-19-1)

    I-Odanacatib (MK 0822) iyisimiso esinamandla kakhulu, esikhethayo nesingathathi hlangothi se-cathepsin K (umuntu / unogwaja) nge-IC50 ye-0.2 nM / 1 nM, futhi ibonise ukuthi ...

    960374-59-8 ONX0914 (PR-957) (960374-59-8)

    I-ONX-0914 (i-PR-957) iyinhlangano ye-immunoproteasome enamandla futhi ekhethiwe ene-cross-reactivity encane ye-protte constitutive.

    ...

    847925-91-1 RO4929097 (847925-91-1)

    I-RO4929097 i-γ secretase inhibitor ene-IC50 ye-4 nM, ivimbela ukucubungula kwamaseli we-Aβ40 no-Notch nge-EC50 ye-14 nM ne-5 nM, inhlonipho ...

    1374598-80-7 I-TAK875 (1374598-80-7)

    I-TAK-875 i-GPR40 i-agonist ekhethiwe ne-EC50 ye-14 nM, i-400 ngokuphindaphindiwe kakhulu kune-oleic acid. I-TAK-875 iyinveli, itholakale ngomlomo, ikhetha ...

    209984-56-5 YO-01027 (Dibenzazepine) (209984-56-5)

    I-YO-01027 (i-Dibenzazepine) i-diphibtidic γ-secretase inhibitor ene-IC50 ye-2.6 nM ne-2.9 nM kuzilinganiso ezingenaselula ze-APPL ne-Notch clevavage ...