Ukubonisa 1-12 of 36 imiphumela

I-CAS CHA. I-PRODUCT NAME ISENDLALELO
    935881-37-1 I-AR-42 (935881-37-1)

    I-AR-42 iyindiza ye-HDAC inhibitor, ibonisa umsebenzi we-biologic ngokumelene nemigqa emincane yesisindo se-mast nge-down-regulation of activated activated ...

    844442-38-2 I-AT7519 (844442-38-2)

    I-AT7519 iyimithi yezinkinobho eziningi ezixhomeke ku-cyclin (CDKs), okungabangela ukuboshwa komakhalekhukhwini, ukufakwa kwe-apoptosis, ne-inhibi ...

    602306-29-6 I-AZD5438 (602306-29-6)

    I-AZD5438 iyinhibitha enamandla ye-CDK1 / 2 / 9 ne-IC50 ye-16 nM / 6 nM / 20 nM. Kuyinto encane kakhulu ku-CDK5 / 6 futhi ivimbela i-GSK3β. Isigaba 1.

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    865783-99-9 I-Briciclib (865783-99-9)

    I-Briciclib i-benzyl styryl sulfone analog, ne-disodium phosphate ester prodrug ye-ON 013100, enezinto ezinamandla ezingasebenzi.

    ...
    1421693-22-2 I-CDKI-73 (1421693-22-2)

    I-CDKI-73 i-CDK9 inhibitor enamandla ne-Ki ye-4 nM. Ibonisa ubuthi olukhethiwe kumaseli we-CLL (LD50 = 80 nM) ngokubhekisele kumakhalekhukhwini wejwayelekile B kanye ne-CD34 evamile ...

    199986-75-9 CVT-313 (NG-26) (199986-75-9)

    I-CVT-313 yi-inhibitor enamandla kakhulu, ekhethiwe, eguquguqukayo, ne-ATP-ye-CDK2 (IC50 = 0.5 UM ye-Cdk2 / A ne-Cdk2 / E; 4.2 UM kaCdk1 / B; 21 ...

    779353-01-4 I-Dinaciclib (SCH727965) (779353-01-4)

    I-Dinaciclib (SCH727965) iyinhlangano ye-CDK inhibitor enomlando futhi enamandla ye-CDK2, CDK5, CDK1 ne-CDK9 ne-IC50 ye-1 nM, i-1 nM, i-3 nM ne-4 nM, ngokulandelana ...

    942918-07-2 I-GSK1070916 (942918-07-2)

    I-GSK1070916 i-Aurora B / C kinase inhibitor enamandla kakhulu (ene-IC50 ye-3.5 nM / 6.5 nM) enomsebenzi obanzi wokuvimbela ama-cell muscu ...

    1346546-69-7 I-GSK872 (1346546-69-7)

    I-GSK872 yi-receptor ehlanganyela iprotheni kinase-3 (RIP3) inhibitor. I-GSK872 inqanda i-TNF- ne-necrosis eyenziwe ngegciwane ku-3T3-SA fibroblasts. ...

    443797-96-4 I-JNJ7706621 (443797-96-4)

    I-JNJ-7706621 i-pan-CDK inhibitor enamandla kakhulu ku-CDK1 / 2 ne-IC50 ye-9 nM / 4 nM futhi ibonisa> ukukhethwa kwe-6-CDK1 / 2 kuno ...

    1073485-20-7 I-LDC000067 (1073485-20-7)

    I-LDC000067 i-CDK9 inhibitor ekhethiwe kakhulu nge-IC50 ye-44 nM, 55 / 125 / 210 /> 227 /> Ukukhethwa kwe-227-fold over CDK2 / 1 / 4 / 6 / 7 ....

    1453834-21-3 I-LDC4297 (1453834-21-3)

    I-LDC4297 iyi-CDK7 inhibitor inoveli (IC50 = 0.13 ± 0.06 nM ye-CDK7 kuya kwe-IC50 phakathi kwe-10 nM ne-10,000 nM yazo zonke ezinye amaCDK ahlaziywe).

    ...