Ukubonisa 1-12 of 37 imiphumela

I-CAS CHA. I-PRODUCT NAME ISENDLALELO
    552325-73-2 A-674563 (552325-73-2)

    I-A-674563 iyinhlangano enamandla kakhulu, etholakala ngomlomo nge-Akt1 inhibitor enenani le-IC50 le-11nM. Iphinde ibonise umsebenzi olwa no-PKA no-CDK2 ngenani le-IC50 ...

    1047634-63-8 I-Afuresertib (GSK2110183) (1047634-63-8)

    I-GSK2110183 iyinhlangano ye-bioavailable yomlomo, ekhethayo, i-ATP-ukuncintisana futhi enamandla kakhulu-i-Aktinhibitor nge-IC50s ye-0.08 / 2 / 2.6 nM ye-Akt1 / Akt2 / Akt3 ...

    487021-52-3 I-AR-A014418 (487021-52-3)

    I-AR-A014418 iyinhlangano ye-ATP yokuncintisana, nekhethiwe ye-GSK3β ne-IC50 ne-Ki ye-104 nM ne-38 nM, ngaphandle kokuvinjelwa okukhulu kwe-26 ok ...

    1056901-62-2 I-AT13148 (1056901-62-2)

    I-AT13148 iyinveli, i-oral multi-AGC kinase inhibitor enomsebenzi omkhulu we-pharmacodynamic ne-antitumor; I-AKT, i-p70S6K, i-PKA, i-ROCK, ne-SGK inhib ...

    857531-00-1 I-AT7867 (857531-00-1)

    I-AT7867 yi-inhibitor enamandla kakhulu ye-ATP-Akt1 / 2 / 3 ne-p70S6K / PKA nge-IC50of 32 nM / 17 nM / 47 nM ne-85 nM / 20 nM, ngokulandelana; okuncane ...

    612487-72-6 I-AZD1080 (612487-72-6)

    I-AZD1080 iyinhlangano ye-GSK3 ekhethiwe, yomlomo, esebenzayo, esebenzayo ngomlomo, evimbela i-GSK3A yabantu ne-GSK3β nge-Ki ye-6.9 nM ne-31 nM, eqondene ...

    486424-20-8 I-AZD2858 (486424-20-8)

    I-AZD2858 iyinhlangano enamandla kakhulu ye-GSK-3 ene-IC50 ye-68 nM. I-AZD-2858 ivimbela i-tau phosphorylation kwisayithi le-S396, futhi isebenza ku-Wnt s ...

    1143532-39-1 I-AZD5636 (1143532-39-1)

    I-AZD5363, eyaziwa nangokuthi i-Capivasertib, i-inhibitor yomlomo etholakalayo ngomlomo we-protein serine / threonine kinase i-AKT (i-protein kinase B) enepote ...

    188011-69-0 I-Bikinin (188011-69-0)

    I-Bikinin (i-Abrasin) inhibitor enamandla yesitshalo GSK-3 / Shaggy-like kinase; ivuselela ukukhonjiswa kwe-BR ngaphesheya kwe-BR receptor.

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    1007207-67-1 I-CH5132799 (1007207-67-1)

    I-CH5132799 inqanda i-PI3K yeklasi, ikakhulukazi i-PI3Kα ne-IC50 ye-14 nM; okuncane kakhulu ku-PI3Kβδγ, ngenkathi izwela ku-PIK3CA mutations cell lin ...

    252935-94-7 I-CHIR-98014 (252935-94-7)

    I-CHIR-98014 i-GSK3 inhibitor ekhethiwe nge-IC50 ye-0.65 nM ne-0.58 nM ye-GSK-3α ne-GSK-3β; I-potentiate insulin yokusebenza kwe-glucose tr ...

    915019-65-7 I-Dactolisib (BEZ235) (915019-65-7)

    I-BEZ235 (NVP-BEZ235) i-PI3K kanye ne-MTOR inhibitor yokuncintisana ye-ATP ye-p110 /// ne-MTOR (p70S6K) ne-IC50 ye-4 nM / 5 nM / 7 nM / 75 nM / 6 nM, futhi ...