Ukubonisa 1-12 of 630 imiphumela

I-CAS CHA. I-PRODUCT NAME ISENDLALELO
    856925-71-8 (-) - iBlebbistatin (856925-71-8)

    (-) - I-Blebbistatin iyi-inhibitor yeselula engenawo umzimba i-myosin II ATPase ne-IC50 ye- ~ 2 μM, ayivimbeli i-myosin light chain kinase ...

    1268524-70-4 (+) - JQ1 (1268524-70-4)

    (+) - I-JQ1 iyinhibitha ye-BET bromodomain, ne-IC50 ye-77 nM / 33 nM ye-BRD4 (1 / 2), ebophezela kubo bonke ama-bromodomains omndeni we-BET, kodwa hhayi ukuze i-brom ...

    5142-23-4 3-Methyladenine (3-MA) (5142-23-4)

    I-3-Methyladenine iyimithi ye-class III i-phosphatidylinositol 3-kinase (i-PI 3-kinase) .Ingavikela ama-granule ama-cerebellar avela kuma-apoptos ...

    1668553-26-1 A-1210477 (1668553-26-1)

    I-A-1210477 iyinhlangano enamandla futhi ikhetha i-MCL-1 inhibitor nge-Ki ne-IC50 ye-0.454 nM ne-26.2 nM, ngokulandelana,> ukukhetha kwe-100 ngokunye ...

    1527503-11-2 A-366 (1527503-11-2)

    A-366 yi-G9a / GLP i-histone lysine methyltransferase inhibitor enamandla futhi ekhethiwe (IC₅₀ = 3.3 nM). Ikhombisa> ukukhetha kwe-1000-fold for ...

    552325-73-2 A-674563 (552325-73-2)

    I-A-674563 iyinhlangano enamandla kakhulu, etholakala ngomlomo nge-Akt1 inhibitor enenani le-IC50 le-11nM. Iphinde ibonise umsebenzi olwa no-PKA no-CDK2 ngenani le-IC50 ...

    844499-71-4 A-769662 (844499-71-4)

    I-A-769662 iyinhlangano yomshini wokuqalisa we-AMP-esebenzayo we-AMP-esebenzayo osebenza nge-EC50 ye-0.8 μM.A-769662 ekhombisa ukukhetha ku-β ...

    934162-61-5 A-966492 (934162-61-5)

    I-966492 iyi-inhibitor enomlando futhi enamandla ka-PARP1 no-PARP2 ne-Ki ka-1 nM ne-1.5 nM, ngokulandelana.

    1166227-08-2 I-A66 (1166227-08-2)

    I-A66 i-p110α inhibitor ecacile kakhulu futhi ekhethiwe nge-IC50 ye-32 nM,> 100 ukukhethwa kwesikhathi kwe-p110α ngaphezu kwesinye isigaba-I-PI3K isoform ...

    607737-87-1 A77-01 (607737-87-1)

    I-77-01 inamandla kakhulu we-TGF-βRI (ALK-5) inhibitor (IC50 = 34 nM). Ivimbela ukusebenza kwe-TGF-β yokubhalisa. Ivimbela ukuqhuma kwe-TGF-β-okubangelwa i-o ...

    909910-43-6 A83-01 (909910-43-6)

    I-83-01 iyinhibitha enamandla ye-TGF-β uhlobo lwe-receptionor ALK5 kinase, thayipha i-activin / receptor receptor ALK4 bese uthayipha i-receptionor nodal ALK7, ngina ...

    714971-09-2 AC480 (BMS-599626) (714971-09-2)

    I-AC480, eyaziwa nangokuthi i-BMS-599626 isetshenziselwe ukuhlolwa ekutadisheni ukwelashwa kwe-Cancer, i-Metastases, ne-HER2 noma i-EGFR Expressing Advanced So ...

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